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Assignment to the groups was not random, and though the groups did not significantly differ on demographic variables or baseline functioning, this may have been due to inadequate statistical power for cross-sectional analyses; in a larger sample, baseline characteristics might prove to be significant predictors of adherence and change in attention or scholastic performance.
Given a potentially weak and specific effect among BRCA2 mutation carriers, however, analyses in a larger series may be warranted.
However, as the number of matched samples was limited, repetition of these analyses in a larger cohort should be performed.
They went on to perform the same analyses in a larger cohort (n = 71) of patients including a greater number of high-risk/metastatic patients.
Further analyses in a larger data set with a greater number of events may provide narrower confidence intervals, which along with assessment of the hazard ratio will determine the likely clinical significance derived from this panel of markers.
Furthermore, single-center reports regarding outcomes of and indications for simultaneous vs. sequential liver and kidney transplantation in individuals with severe renal and hepatic phenotype [ 29- 31] require analyses in a larger ARPKD cohort as basis for decision-making.
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First follow‐up analyses in a large collection of over 1300 AD families reveal that in addition to APOE genetic variants in ACE, CHRNB2, GAB2, and TF show the most consistent risk effects across a wide range of independent samples and study designs.
We performed three-dimensional live imaging analyses in a large number of specimens (N = 25), and found that afferent neurons formed two types of neurites.
In summary, we report quantitative genetic analyses in a large sample of Virginia families to describe how genetic and environmental factors contribute to differences in variability of gestational age between Americans of European and African ancestry.
We conducted these analyses in a large, well-characterized U.S.-based natural history cohort of HIV-1-positive individuals, whose clinical characteristics have been described before [34], [36], [37], [38], [39].
Standardisation of the protocol is essential to perform reliable analyses in a large multicentre study.
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