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In subgroup analyses, efficacy was higher among subjects that reported that they had previously had unprotected receptive anal intercourse and those that reported greater than 90% compliance with pill use.
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METHODS:Using Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) data, we analysed efficacy and safety outcomes, adjusting hazard ratios (HRs) for potential confounders using Cox regression analysis.
To analyse efficacy, safety and complications of dissociative anesthesia with ketamine plus benzodiazepine in a prehospital setting.
Outcomes in post hoc analyses suggested efficacy in some, but not all subjects, consistent with phenotypic variability of DS.
Formal interim analyses of efficacy will not be conducted.
No interim analyses for efficacy were performed for this study.
No interim analyses for efficacy or futility were done.
Descriptive analyses of efficacy and standard safety summaries were performed.
Secondary and subgroup analyses for efficacy and safety analyses will also be performed.
Fourteen patients completed at least 8 weeks treatment and were evaluable for analyses of efficacy.
These patients were included in all analyses of efficacy end points, including HRQoL and hypoglycemia.
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