Sentence examples for analyses activation of from inspiring English sources

Through unbiased RNA interference screening analyses, activation of the PI3K pathway has been implicated as a major mediator of trastuzumab resistance [ 7].

Analysing activation of the signal transducer and activator of transcription (STAT 3, Akt and MAPK cell survival pathways, we could detect only an activation of Akt as demonstrated by elevated phosphorylated Akt levels under MPP+ lesioning conditions.

Next, we analysed activation of calcium handling proteins that are essential in regulating calcium transient amplitude.

By using Bowes cell lines containing an empty vector or BRAFV600E, we measured expression of MMP-1 and several secreted chemokines and cytokines, and we analysed activation of stromal fibroblasts.

Based on this rationale and the paucity of studies investigating the predictive value of AMPK activation in patients treated with anti-angiogenic drugs, we designed a pilot retrospective study to analyse activation of the AMPK pathway in CRC patients treated with bevacizumab plus chemotherapy and to correlate it with patient clinical data and survival.

Additional whole-brain analyses highlighted activation of other areas besides BA10, consistent with recent proposals that emphasise the role of distributed networks during PM performance.

Our results from in silico, in vitro DNA-binding analyses and activation of wt-Apc, strongly suggest that there is a direct positive regulation of Notch-2 through Wnt-signaling.

For the analyses, the activation of the reading condition could be subtracted from the activation of the other conditions.

To assess whether TNF and IFNG induce autophagy in MSCs, MSCs were cultured in the absence or presence of TNF or IFNG and cells were collected at various time points for analyses of activation of autophagy.

On the basis of molecular analyses showing activation of multiple RTKs in their tumour, four patients with metastatic TCs refractory to conventional therapies were treated with sunitinib according to standard protocols.

It has become clear, thanks to transcriptional analyses that activation of an effector immune response is a multifactorial event that includes the activation of all arms of effector immunity including both innate and adaptive mechanisms and that neither alone is sufficient to induce tissue specific rejection [ 51, 52].