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Although ALDH1A1 was associated with poor outcome in both ER+ (HR 2.5, 95% CI 1.1 to 5.6, P = 0.027) and ER- disease (HR 2.4, 95% CI 1.4 to 4.1, P = 0.002) when complete data were analysed, analysis of imputed data only reproduced the association within ER- disease (HR 1.9, 95% CI 1.1 to 3.2, P = 0.022) and not in ER+ cases (HR 1.6, 95% CI 0.73 to 3.6, P = 0.233).
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Mean PPT data for gender groups, from both studies, were analysed using analysis of covariance with repeated measures, and age as the covariate.
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