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In short, read-across is defined by ECHA as "the use of relevant information from analogous substances (the 'source' information) to predict properties of the 'target' substance(s) under consideration" [106].
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However, in daily life, the occasion of exposure to these analogous chemical substances or induction of genetic modification is uncommon.
The brain and body have evolved over millions of years to recognise and utilise these chemicals, and drugs typically work because they are analogous to the substances that occur naturally in our bodies.
These communications involve substances analogous to a morphogen in the developing embryo that diffuse through the tissue creating a concentration gradient.
The case of tetra-coordinated, tetra-valent and uncharged nitrogen (6.8% of invalid substances) is analogous to the most frequent atom type.
Thomas's term for such names is analogy: 'being' is an analogous term and its primary analogate is substance.
Screening tumour biopsy samples for neuropeptide receptor expression may provide insight into the likelihood of patients responding to treatment with substance P analogues, analogous to oestrogen receptor expression conferring efficacy to tamoxifen in breast cancer.
The observed behavior is analogous to the behavior of paramagnetic substances (e.g spin glasses) which acquire specific macroscopic organization thanks to the existence of preferred orientations of nearby elementary units (e.g. dipoles) [ 7].
And, perhaps, an analogous case can be made for thinking substances, to the effect that that a thinking substance essentially has thoughts does not lead to any obvious conceptual connections that would dovetail nicely with the causal powers traditionally identified as belonging to the mind.
Sustained release of neurotransmitter-like substances occurs in the bladder, analogous to the experimental incubation of the agonists in this study.
In 1813 British chemist Sir Humphry Davy, who was passing through Paris on his way to Italy, recognized substance X as an element analogous to chlorine; he suggested the name iodine from the Greek word ioeides, "violet coloured".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com