Sentence examples for analog structures from inspiring English sources

While the parent taranabant bears highly potent binding affinity to cannabinoid CB1 receptor, neither of the analog structures improved CB1 receptor binding affinities.

As already mentioned, ligand-based VS suffers from the bias caused by enrichments of analog structures.

This allowed the definition of a set containing 34 minimal acyclic riboside analog structures (Fig. 12).

The relationship between the GH-releasing potency and the analog structure is discussed.

Thus, strontium in zeolites is a good analog structure for inner-sphere complexation of strontium on silica gel, if it occurs.

The ligands in the analog structure were then transferred to the model, and the fitness of the ligand-model complex (BS-score) was calculated by comparing the local structure and sequence similarity in the binding site region.

Recently we reported that betaine-type metabolite analogs structure-dependently facilitate enzymatic hydrolysis reaction for α-glucosidases, β-glucosidases, and alkaliphosphatases.

This indicated that the N-terminal protective group may not play an important role in the activity and the analogs structure could be simplified to pentapeptide analogs while retaining good aphicidal activity.

A variety of analog inhibitor structures were used by Xie et al. [ 1] to show that the minimal structure for binding at the substrate-binding site of P. stutzeri TyrA c is a six-membered ring with a 4-hydroxy substituent.

The approach is demonstrated in analog circuit structures for the United Microelectronics Corporation 130 nm design process.

The developed tool, AIDA-C, implements the proposed approach, and is validated for both classical and new analog circuit structures using the UMC 130 nm design process.