Exact(1)
A randomized, open-labeled, crossover study compared the analog premixed insulin Humalog Mix 25 (Eli Lilly) with the nonanalog premixed insulin Humulin M3 (Eli Lilly), and, given in identical doses, the analog preparation showed somewhat better postprandial blood glucose control after Iftar and lower rates of hypoglycemic events.
Similar(59)
Five insulin analog preparations have become commercially available: two long-acting analogs (insulin glargine and detemir) and three rapid or fast-acting analogs (insulin lispro, aspart and glulisine).
This article highlights the specific properties of these new insulin analog preparations and focuses on their potential advantages and disadvantages when used in children with diabetes mellitus.
Given the high and increasing costs of insulin, it behooves us to examine whether analog preparations are worth their extra costs.
53 In the absence of clear and distinct advantages of the newer analog preparations, it is difficult to justify shifting patients from the well established, universally available, and cheaper nonanalog insulin preparations.
The remainder of this review discusses insulin analog preparations that are designed to possess a protracted action, with a focus on insulin glargine, which was the first 'long-acting' insulin and was approved for clinical use in 2000.
46 In nonfasting patients, several studies failed to show significant advantages in glycemic control (HgA1c) or the rates of hypoglycemia when nonanalog insulin preparations (neutral protamine Hagedorn, Humulin N; Eli Lilly; Indianapolis, IN) were compared with the recently introduced and more costly analog preparations (glargine and detemir) when used in combination with oral agents.
LAIAs were developed to achieve this result, by using simple titration schedules, while avoiding the wide pharmacological variability of traditional long-acting non-analog insulin preparations.
I like analog analogies.
This paper reviews the utility of analog environments in preparations for a Europa lander mission.
This facilitates preparation of analogs for intricately specified treatments.
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