Sentence examples for an upregulation in the expression from inspiring English sources

(a) The RT-qPCR analysis showed an upregulation in the expression of SOX-2, OCT-4, KLF-4, Nanog, Lin-28A and CD133 in a time-dependent manner in sorted A549 cells under hypoxic conditions (*P<0.05).

We observed a change, an upregulation, in the expression of a peptide associated with the statocyst.

Moreover, the loss of one of the PKB isoforms was not compensated by an upregulation in the expression of any of the other isoforms (Figure 1B, bottom panel).

At the same time, we found an upregulation in the expression of the early premyogenic progenitor marker, Pax3, in the dermomyotome-derived premyogenic cells.

Several different studies have reported an upregulation in the expression of Wnt ligands and β-catenin in cancer cells compared with normal prostate cells (McKiernan and Benson, 2004; Ricke et al, 2008).

This often involves an upregulation in the expression of pro-angiogenic factors, such as vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), platelet-derived growth factor (PDGF) and type II fibroblast growth factor (FGF2) (Folkman, 1995).

Investigation of the expression of known HIF1 target genes VEGF and GLUT-1 showed an upregulation in the protein expression after 1 h of E2 stimulation, exhibiting the significance of E2 modulation on HIF1 activity.

Genetically altered mice with additional deletion of the MIP-1α/CCL3 gene demonstrated an upregulation in the chemokine mRNA expression paralleled by comparable cytokine expression following RSV infection, compared with wild type mice.

Apoptotic stimuli such as oncogene inhibition or treatment with chemotherapeutic agents cause an acute upregulation in the expression of Par-4 in these tumor cells, leading to Par-4-induced ZIP-kinase-dependent MLC2 phosphorylation, multinucleation, and ultimately apoptosis due to cytokinesis failure.

Histopathology confirms the infiltration of leucocytes and there was a marked upregulation in the expression of genes relevant to infiltration.

These findings demonstrated a significant upregulation in the expression level of ES cell-specific genes and inhibition of an endodermal marker.