Our aim throughout the development of CREST has been to translate updated experimental findings into a manualised 10 session individual treatment package.
We put forward a spatio-temporal model of coupled GRNs that integrates updated experimental evidence for cell-fate determination in Arabidopsis epidermis and incorporates cellular communication, domain characteristics (size and boundary conditions) and cell shape.
Updated experimental results on the linac laser synchronization and laser plasma linac are presented.
This article unifies preliminary work by the authors[40, 41], presents previously unpublished aspects of the proofs, and contains updated experimental results.
Many of the strains used are from the Burkholderia cepacia complex experimental strain panel and updated experimental strain panel [ 29, 87].
Here we have modelled the meta-GRN by integrating the updated experimental data into models that explicitly consider GRNs coupled via cell-to-cell communication in a cellularised domain.
It is not completely surprising, as the just mentioned test seems to suggest, that absolute indices based on the architecture of the empirical network may go differently as compared to qualitative indicators assigned from updated experimental information.
Herein, the development of a cyber-physical real-time model updating experimental platform, including real-time computing environment, model updating algorithm, hardware architecture and testbed, is described.
In this paper, we continue to extend this model by adding interactions according to updating experimental findings.
In all, through extending the models of Bcl-2 apoptotic switch based on updating experimental findings, we successfully identified two independent positive feedbacks which contribute to the switch mechanism in Bax-activation.
