To validate the Thy-1-mediated regulation of TNF-α-activated gene expression, we transiently transfected Thy-1− MEFs with either a backbone vector or a Thy-1 expressing vector.
However, the late occurrence of Aβ deposits was mentioned in two lines (as briefly and incompletely described in the literature) in which hAPP, without mutation, was overexpressed under the control of a NSE [ 130] or a Thy-1 promoter [ 128].
These were evaluated by SEM, in vitro neuronal, Schwann and dorsal root ganglion culture and in vivo using a thy-1-YFP-H mouse common fibular nerve injury model.
The recent report is noteworthy that the specific overexpression of type-1 NRG1 driven by a Thy-1 promoter in brain projection neurons markedly impairs PPI [38].
In this study, by using a transgenic rat expressing ChR2 specifically in the RGCs under the regulation of a Thy-1.2 promoter, we tested the possibility that direct photoactivation of RGCs could restore effective vision.
Both lines express 1N4R tau under a Thy-1 promoter, similar to Tau4RTg2652.
Juvenile testis cell suspensions stained with a THY-1 antibody contained two discrete cell populations, designated THY-1+ and THY-1− (Fig. 1A).
FACS analysis identified a THY-1+ fraction of rhesus testis cells that was enriched for consensus SSC markers (i.e. PLZF, GFRα1) and exhibited enhanced colonizing activity upon transplantation to nude mouse testes.
A TEXT… Thy word is a lamp unto my feet, and a light unto my path.
Not an eye / But is a-weary of thy common sight".
Her rapists mock the silence they inflicted: "So, now go tell, an if thy tongue can speak, / Who 'twas that cut thy tongue and ravish'd thee".
