For all optimization trials, each sample is analyzed in either triplicate or quadruplicate.
For all optimization trials, each sample is analyzed in quadruplicate, so each final sample preparation is 200 μl in each case.
As shown in Figure 3-A, the objective function value f of each optimization trial decreased with respect to tolerance adjusted at each optimization restart.
Later, similar results were published by Fenwick [ 8] based on the Wilson optimization trial [ 9].
The first optimization trial starts with "sufficiently relaxed" tolerances both placed on parameters and objective function, e.g., of 100.
When starting from the same initial guess applied to the optimization trial in Figure 4, the fastest convergence speed was obtained when α is fixed at 10 (about 200 s for f < 10-14).
Here, we suggest a method to adjust tolerance values and find a proper value by repeatedly restarting optimization trials.
Neither the VV optimization trials nor the high-precision optimization studies, therefore, support an important role for resynchronization of the ventricles as the main benefit of biventricular pacing.
During the optimization trials, these values for critical factors were varied between the extreme levels.
Following optimization trials of the picosecond laser cleaning parameters on model leather samples, satisfactory removal of the soiling over the historical leather surface is achieved.
