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The developed hull form optimization tool is applied to the hydrodynamic design optimization of a Series 60 model, and model tests are carried out on the original and an optimised model at WHUT (Wuhan University of Technology) for validation.
The resulting knowledge is automatically merged and organised into a single common SOHN for which we can apply the same prediction and SAR analysis tools, allowing the end user to access an optimised model for both predictive and knowledge discovery purposes (Figure 25).
This resulted in the selection of an optimised model, which shows a good fit to the measured time series data (J=0.0833) and contains 8 known interactions.
The peak values of this distribution were used to create an optimised model, named PKA Model B, whose simulation is shown by the red trace of Figure 2 (panel A).
Here we describe the use of PNAs incorporating a series of arginine residues in their backbones as polyarginine mimics either at the C2 or at the C5 positions potentially able to perform specific inhibition of miR-210 in the K562 and other cellular lines, with the aim of developing an optimised model for cellular uptake, biostability and anti-miR activity.
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In addition, an optimised PMLG model is designed and simulated.
The neural network design itself was also subjected to simulated annealing to obtain an optimised predictive model.
Improvements in form of an optimised business model can relate to each of the generic elements of the transport chain and/or to the coordination between these elements.
A central composite design (CCD)–response surface analysis (RSA) was carried out and the resulting optimised model solutions confirmed the results.
This procedure resulted in a table of occurrence frequencies for each interaction of the optimised model (Additional file 2).
The optimised model was able to predict fruit surface temperature with a root mean square error of 2 4 °C.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com