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This suggests an ongoing pathological process.
Like NTproBNP/BNP, the circulating TnI/TnT level is not pathogenic and specific and can be viewed as a signal of an ongoing pathological process in the heart.
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Recent evidences reveal that many of the fibrotic lung diseases involve AECs both as a frequent target of injury and as a driver of ongoing pathological processes.
The elucidation of genetic disorders leading to fibrotic disease and the numerous studies of mouse models of fibrotic lung disease have revealed that many of the fibrotic diseases involve the epithelium both as a frequent target of injury and disease initiation and as a driver of ongoing pathological processes [ 1, 17].
Thus, AAbs may be directly involved in the induction of pathogenic processes or could be related to the progression over time of ongoing pathological processes in the retina and optic nerve.
Whether these genes are causally involved in the mechanisms linking smoking to the development of atherosclerotic plaques or whether they are only markers of ongoing pathological processes remains to be elucidated.
There is a growing consensus that the CSF is the best material for biomarker discovery and for understanding the ongoing pathological processes associated with neurodegeneration [ 38, 39].
Molecular imaging thus provides important insight into the ongoing pathological processes in AD in relation to clinical symptoms and disease progression.
Second, the inclusion of cognitive reserve variables along with pathology variables allowed us to measure the beneficial effect of cognitive reserve against cognitive decline due to ongoing pathological processes.
We can postulate that the impact may accelerate a pathological process already ongoing or precipitate a detrimental tissue response that ultimately triggers the disease in genetically susceptible individuals.
Thus, RT is an important pathological process across psychological disorders.
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