The phrase "an obvious difficulty of" is correct and usable in written English.
It can be used when discussing a clear or apparent challenge or problem related to a specific subject or situation.
Example: "One obvious difficulty of implementing this new policy is the lack of employee training."
Alternatives: "a clear challenge of" or "an evident issue with".
The phenomena that more DIF exists in the Activity domain of SGRQ may be caused by an obvious difficulty gradient of underlying physical function.
But there is an obvious difficulty involved in this kind of aspirational imperialism.
Although we measured the enterprise growth with the time to IPO, this measure presents an obvious difficulty in showing unique and diverse stages of entrepreneurial growth, contingent on corporate conditions and decisions.
An obvious difficulty in establishing the extent of the obligation to research is the open-ended nature of research: when can we say, with respect to research, that 'the job is done'?
Experts noted the obvious difficulty of using a standardized test to compare countries and cities of vastly different sizes.
Our concern about that kind of solution (aside from the, perhaps obvious, difficulty of reaching a consensus), is that the field may not be mature enough to put any of these questions to bed, and given that it would be damaging to the legitimacy of the empirical bioethics endeavour to try to avoid them.
In addition to the obvious difficulty of applying a United Kingdom-based model to the South African setting, it is also probable that the treatment of diabetes, and its co-morbidities, has improved substantially since the engine was developed (the intervention trial on which the engine is based was completed in 1997 and the post-trial programme ended in 2007) [ 43].
Offsetting this advantage of the circular tree is the obvious difficulty of extracting specific information about the relationships among a subset of taxa of interest from this representation.
One obvious difficulty of this type of analysis is that the cell populations are altered in the testes of hsp90αgt/gt mutant animals with ultimately a very severe depletion of germ cells relative to somatic cells.
