Sentence examples for an obstacle to the optimization of from inspiring English sources

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Lack of specificity of anti-KLK antibodies, especially their crossreactivity with multiple KLKs, has been an obstacle to the optimization of immunoassays for clinical applications.

Similar(59)

The low incidence of ILD-associated ARF requiring ICU admission is a major obstacle to the assessment of outcome predictors and treatment optimization.

Applying obstacles to the shape optimization problem is on the other hand not very common.

Thermochemical pretreatment processes have been developed to address the challenge of biomass recalcitrance, however the optimization, cost reduction, and scalability of these processes remain as obstacles to the adoption of biofuel production processes at the industrial scale.

Several different thermochemical pretreatment processes have been developed to address this challenge, however the optimization, cost reduction, and scalability of these processes remain as obstacles to the adoption of biofuel production processes at the industrial scale [ 3].

These obstacles have led to a misunderstanding of the basic effects of the BTO etching process and have hindered the optimization of this process.

In the design of multistream plate-fin heat exchangers (MPFHEs), surface selection and layer pattern optimization have been investigated as two independent problems and still remain at the empirical stage, which becomes an obstacle for optimizing the performance of MPFHEs.

In this paper we consider two-dimensional CFD-based shape optimization in the presence of obstacles, which introduce nontrivial proximity constraints to the optimization problem.

A more general and less restrictive alternative to deal with this obstacle is to compute several times the optimization algorithm using different choices of initial points and keep the best solution to the optimization problem as our final function.

Three geometric variables (the ratio of the obstacle height to the height of the duct; the ratio of the transverse pitch to the base length of the obstacle; and the angle of attack) were used as design variables for the optimization.

Lacking powerful optimization method is the key obstacle to solving this problem.

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