Sentence examples for an obstacle in the development of from inspiring English sources

This drug is characterized by poor water solubility, which represents an obstacle in the development of a parenteral formulation.

However, the problem of nonspecific amplification of relaxed circular DNA (rcDNA) is a major obstacle in the development of an accurate cccDNA quantification assay.

34– 36 Hypoxia-induced MDR is a major obstacle in the development of effective cancer therapy.

Parasite evolution can be a key obstacle in the development of any effective disease control programmes.

From a drug development perspective, toxic liver injury can lead to drug withdrawal from the market and represents a large obstacle in the development of pharmaceuticals.

In vivo transgene silencing is frequently reported and is currently considered as a major obstacle in the development of ex vivo gene therapy protocols using stem cells.

The lack of well-defined targets specific to dormancy phase M. tuberculosis has been a major obstacle in the development of effective short-course therapies.

A major obstacle in the development of new treatments for severe asthma is the heterogeneous pathogenesis of the disease, which involves multiple mechanisms and cell types.

The greatest obstacle in the development of antisense or antigene PNA for therapeutic use is efficient delivery into cells.

"Mao had an excessive belief in class struggle, and that became an obstacle to the development of productive forces," Mr. He said.

However, the high genetic diversity found in M. fijiensis[ 9, 10] may represent an obstacle to the development of resistant plants because resistance may be quickly superseded.