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It is an obstacle against which the science of the human body has always had to struggle.
This large amount of highly homologous tandemly repeated DNA presents an obstacle against understanding the organization of chromatin domains at human centromeres.
Hence, although CC has also shown many beneficial medicinal properties, its' coumarin content is likely to be an obstacle against regular use as a pharmaceutical agent, unlike in the case of CZ.
Another explanation was the so called "heteroresistance" that means the presence of mixture of susceptible and resistant subpopulation in culture which could be an obstacle against the sensitivity of molecular drug resistance testing and the successive therapy[ 21].
Moreover, the data presented in this study suggested that rapid re-accumulation of hydrosalpinx fluid is an obstacle against successful implantation and the cause of lower success rate with ultrasound guided aspiration of hydrosalpinx fluid compared with salpingectomy.
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A lack of medical knowledge was also mentioned as an important obstacle against a broader involvement of the practice nurse in this area.
The insulation of a reactor cavity wall serves as a dominant obstacle against a heat transfer from the reactor vessel to the surrounding ground when the RCCS fails to operate.
A planetary ionosphere forms an effective obstacle against the solar wind flow which, in turn, forms a bow shock.
Their survival tactics often involve glycoconjugates that form a protective obstacle against unwelcoming forces.
However, the security threat in terms of Denial of Service (DoS) attacks constitutes a major obstacle against the achievement of this transfer.
However, a major obstacle against the clinical application of this targeting strategy has been the poor penetration of the targeted payload through the vascular wall and into the tumor parenchyma, especially in solid tumors, which have a high interstitial pressure [ 11, 12].
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