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The phrase "an marked decrease" is not correct in written English.
It should be "a marked decrease" because "marked" begins with a consonant sound.
Example: "There has been a marked decrease in sales this quarter compared to the last."
Alternatives: "a significant decrease" or "a noticeable decrease."
Exact(1)
Knockdown of UTX in differentiating myoblasts leads to an marked decrease in both Myog and CKm expression while having no effect on expression levels of the ubiquitously expressed DDX5 gene.
Similar(59)
A recent article describes a marked decrease in the levels of ferroportin in breast cancer.
Sufentanil-midazolam anaesthesia caused a marked decrease in respiratory rate and marked hypercapnia.
"This was a challenging quarter, as we saw a marked decrease in client activity and declining asset valuations," Mr. Blankfein said.
As a result, the redox potential showed a marked decrease.
In these patients there was a substantial increase in weight together with a marked decrease in eating disorder psychopathology.
We found a marked decrease in keratometry with age, and an increase in CCT with age.
This probably reflects an influence on proliferation as most tumours (82%) show a marked decrease in the proliferation marker, Ki67.
MMA results in a marked decrease in WASO and increase in REM, and to a lesser extent NREM sleep.
However, a marked decrease in TS expression was seen upon treatment with a CDK4 inhibitor.
However, there has been a marked decrease of that in recent years.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com