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This "novel" condition alone cannot be used to attribute a causal role to these variants; in fact, any dataset of either healthy or unhealthy individuals will contain an large proportion of private variants, even taking into account the fact that there are more than 8700 complete or semi-complete genomes available in the literature to date (http://www.phylotree.org/).org/
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CEO of Professional Science Editing for Scientists @ prosciediting.com