I strongly suspect he believed that Coffee's problems were a natural and irreversible consequence of aging; something that he had to accept.
And here we are not dealing with an advantageous result that may be burdened by the presence of some unpleasant side effects but we are faced with the probability of a potentially detrimental and irreversible consequence of treatment combined with absence of the desired outcome.
The absence of effective treatment to the intracellular pathogen and the irreversible consequence of infection makes the need of a specific vaccine urgent.
Also, we suggest, early in the course of the disease, the use of IL-1 receptor antagonist as a therapeutic option to chronic papilledema in order to prevent irreversible consequence of chronic excessive intracranial pressure and final optic atrophy.
This reflects the irreversible consequence of nuclear GSH depletion early in the culture and could account for the persisting lower growth rate of DEM treated cells (Fig. 1), despite the important increase in total GSH level.
With the country on the precipice of becoming a nuclear power, undermining the democrats–our last best hope may prove a mistake with irreversible consequences.
Uncertainty in the economy, expensive and deadly wars in Iraq and Afghanistan, 45 million people without health insurance, high unemployment, financial and corporate disasters, a climate crises with irreversible consequences, record budget deficits and a broken political system that exacerbates the problems because too many politicians care more about their own re-election than solving problems.
Provided a car vessel bursts, irreversible consequences will surface.
A stay pending appeal is necessary to prevent these far-reaching and irreversible consequences of a profoundly flawed ruling.
With such devastating and irreversible consequences, gaining an understanding of the genetic risk factors for NTDs is of prime importance because it could pave the way towards improved genetic counselling for parents, and identification of novel primary preventive therapies.
