Sentence examples for an intermediate marker of from inspiring English sources
The potential of the aromatase gene functioning as an oncogene within the breast may be tied to breast density which in turn may represent both a selection tool for elevated risk and an intermediate marker of prevention.
In conclusion, our findings suggest that monitoring plasma celecoxib concentrations may provide a method to determine response to a an intermediate marker of breast cancer.
Both of these findings support the validity of short-term changes in Ki67 as an intermediate marker of the clinical effectiveness of endocrine therapy.
These data are important firstly because they add further validity to changing Ki67 at 2 weeks being an intermediate marker of effectiveness, thereby supporting the use of this marker for drug development and studies of mechanisms of resistance.
Because of its inverse association with hyperglycemia, 1,5-AG is generally thought to have utility as an intermediate marker of glycemic control (25) or to monitor postprandial hyperglycemia (8, 9).
It is important to note that Ki67 has been validated as an intermediate marker of long-term benefit from endocrine treatment [ 27] and, in this respect it is a better endpoint than clinical response per se.
The strong link between postmenopausal estrogen levels and breast cancer risk suggests the possibility that plasma estrogen levels may be a useful intermediate marker of prevention.
We recently published a similar study (case-control) (4) that showed that the presence of CD is also associated with an increased intima-media thickness of the carotid arteries, a well-known intermediate marker of endothelial dysfunction and macrovascular disease.
It is incumbent on us to agree that some intermediate marker of risk must be used to show the probable effect of a regimen.
It is therefore incumbent on us to agree that some intermediate marker of breast cancer risk must be used to show the probable effect of a regimen and then, if this shows that the regimen affects the intermediate marker in a manner to suggest increased breast cancer, that we act accordingly.
To the best of our knowledge, associations between Lp(a) and intermediate markers of CVD risk have not previously been reported for young African American children.
