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The results show that when listeners are involved in auditory spatial attention tasks an interacting network of frontal, temporal, and parietal regions is activated.
However, a recent view provided by [ 10] denies the necessity of stabilizing selective pressure to attain robustness for a system that can be represented as an interacting network.
Among the predicted miR-30 targets, we focused on four genes, which were identified as part of an interacting network by Cytoscape (Supplementary Figure 7) and thus considered high-confidence predictions.
In the present work, we focus on the AP-1 family of TFs and particular members of this family are regulated in an interacting network, and the consequences on downstream target gene expression of TH.
The key assumption during prediction of interactions between TFs and their target genes using gene expression data is that high dimensional mRNA expression profiles contain hidden regulatory signals, which can be decomposed to low-dimensional regulatory signals driven through an interacting network [ 87].
We found that the SZ-GWIS genes are part of an interacting network centered on SMARCA2 (Loe-Mie et al., HMG, 2010).
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For instance, local duplication of a gene whose product is involved in a large interacting network will generate supernumerary duplicates that will disturb the network stoichiometry (gene dosage principle).
We consider three cases: one neuron with two weights and two stimuli, one neuron with two weights and three stimuli, and finally a weakly interacting network of neurons.
Altogether, we conclude that our combined data are a strong indication for the involvement of the TLR signaling pathway in the response to vaccination, as well as for the cooperation of its genes in a functional interacting network.
All these genes form a complex interacting network.
Regional invasiveness and distant metastasis of ampullary cancer is controlled by a complex interacting network.
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