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A reference voltage shift of only 7.6 mV (around 1.1%) was measured after irradiation with 10 keV X-rays up to an integrated dose of 225 Mrad (SiO2).
At a "read" current of 160 μA an average shift in voltage of 51±4 mV was measured at an integrated dose of 30 rad with a temperature coefficient of 2.3±0.3 mV/°C.
Electronic recording of the dosing history using a device with an integrated dose log offers an improved, objective method of accurately monitoring adherence.
Moreover, when multi-shot irradiations were performed, the overall time needed to obtain an integrated dose of several Grays again overlapped with the multi-scale dynamics of biomolecular damage repair sequences and cell signalling steps.
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For the SIB a daily integrated dose of 0.4 Gy was delivered, giving a total dose of 60 Gy to the initial tumor bed.
With the developments in dosimetry software, an integrated boost dose within another dose volume can be calculated.
Thus, DLP is an indicator of the integrated dose of an entire CT examination.
Parameters such as charge-to-voltage conversion gain, pixel leakage current, noise and charge collection efficiency are investigated as a function of integrated dose.
However, to our knowledge, the current analysis is the first example of a simulation framework for efficacy evaluation that integrated dose reductions in a somewhat more explicit and mechanistic fashion, potentially allowing more flexible use when evaluating alternative scenarios.
In the trial, patients are randomized to either conventional chemoradiation treatment (60 Gy in 30 fractions) or metabolically adaptive chemoradiation, where FDG-avid tumor subvolumes receive an integrated boost dose to a maximum of 85 Gy in 30 fractions.
In our study, we evaluated an integrated smoking dose as pack-years.
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