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All can play valuable roles in supporting an integrated change effort.
This paper presents an integrated change management system developed to represent the key decisions required to implement changes and to simulate the iterative cycles of concurrent design and construction resulting from unanticipated changes and their subsequent impacts.
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Although in many areas of the world the impacts of climate change are likely to be determined by highly-localized physical, biological and human factors, quantifying the magnitude of integrated change across a suite of physical climate indicators can help to identify climate change "hotspots" that show the strongest and most robust aggregated response to global-scale warming.
Growth response to dark is part of an integrated developmental change throughout all the plant organs [ 60].
The accompanying hypotension was again slower in onset but the integrated change was not different from the control.
In short, the PSA coefficients quantify the integrated change in the system behaviour due to persistent parametric perturbations, and thus the dynamical information of when a parameter perturbation matters is lost.
Studies of contemporary land-cover change require an integrated approach because changes in cover and environmental conditions are primarily caused by land uses, which, in turn are governed by human driving forces in a specific socio-economic and cultural context.
Results reported here provide a novel gene derepression mechanism, emerging from integrated changes in the levels of cytosine methylation and histone acetylation, which control IL-8 transcription.
Hence, the sensitivity coefficients at time t represent an integrated or accumulated change in the states from τ to t due to a persistent parameter change started at time τ (see Figure 3(b)).
Isolated perfused hearts were used to study the effects of a decreased oxygen concentration in the perfusate on contractile performance (RPP) and phosphocreatine (PCr) concentration (assessed by 31P-NMR), and to describe the integrated changes in cardiac energetics regulation by using Modular Control Analysis (MoCA).
This work may serve as baseline to broaden our knowledge on the integrated changes on crop fitness and nutritional quality following domestication.
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