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A similar thermal instability was detected in ΔF508 CFTR channels reconstituted in planar bilayers.
The MSI status was determined with standard methods for 223 cases, and a high level of instability was detected in 59 tumours (26.5%, MSI-High), whereas 164 samples showed stable microsatellite repeats (73%, MSS).
In this knee, only 18 months after primary TKR a secondary medial and lateral midflexion instability was detected and required a revision TKR 24 months after the primary TKR.
If instability was detected we proceeded to perform a diagnostic arthroscopy and repaired the ligaments.
In the case of cyanazine, high instability was detected over the whole duration of storage.
No instability was detected in the microsatellite sequence Bat-40.
Microsatellite instability was detected in both colon and mammary tumors induced by PhlP.
As regards the other 57 cancers, no instability was detected at any locus analysed.
Microsatellite instability was detected in 3 out of 26 primary tumours and 4 out of 32 metastatic tumours.
In all cases, microsatellite instability was detected with both markers in the areas of loss of IHC staining.
Minisatellite instability was detected in only one case (1/55, 1.8%), and the frequency of microsatellite instability was low, being found only in three cases (3/55, 5.5%).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com