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MCP-1 is an initiating factor and biomarker of atherosclerotic diseases.
My contributions:One line of research I followed was to investigate the role of founder events, the founding of new populations by one or a few individuals, producing an extreme population bottleneck, as an initiating factor in speciation.
While clinical studies show that a loss of the microvascular circulation precedes and may act as an initiating factor for the development of chronic rejection, preclinical studies demonstrate that improved microvascular perfusion during acute rejection delays and attenuates tissue fibrosis.
Our data support that placentally-mediated reduction in glucose transport is an initiating factor for reduced fetal growth under conditions of chronic hypoxemia.
These authors proposed that sterols are required for cellulose biosynthesis and cell wall construction; one possible mechanism might be via a role for sitosterol as an initiating factor in cellulose biosynthesis [54].
Glucose metabolic disorders are probably an initiating factor.
Similar(27)
Because of the inferior nature of the degeneration, light was considered to be a good candidate for such an additional initiating factor for this type of retinal degeneration.
These results support the hypothesis that, while TNF-α may be an important initiating factor in matrix degeneration, IL-1β plays a greater role in established pathological degradation.
Chronic hyperglycemia is recognized as an important initiating factor for continuous deterioration of β-cell function and mass in type 2 diabetic patients.
An alkaline environment, as in the urea-soaked skin of diaper dermatitis, is an important initiating factor of bacterial and yeast infections, 24 due to the increased growth of pathogens and epidermal barrier abnormality.
Since platelets have been shown to be an important initiating factor for NET formation, the reduced platelet counts in septic mice after 48 hours might explain the reduced NET formation in vivo later during sepsis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com