Sentence examples for an initial single dose of from inspiring English sources

We suggest an initial single dose of 4 units (14) of insulin administered with the largest meal; for patients taking < 40 units/day of basal insulin, a starting dose of 3 units may be more appropriate.

An initial single dose of aminoglycosides was commonly subsequently replaced by fluoroquinolones to limit harmful side-effects.

A good response was bleeding that stopped following the initial single dose of 180 or 150 μg kg−1 rFVIIa; a partial response was bleeding that stopped following a second dose of 90 μg kg−1 rFVIIa; and a lack of response was characterized when bleeding symptoms persisted after administration of two doses of rFVIIa.

The SIMPLIFI Phase II trial included 302 patients who were randomized to one of three treatment arms: the daily-dose arm (200 mg for 3 to 7 days), the single-dose arm (1,200 mg once), or the infrequent-dose arm (initial single dose of 800 mg, followed by reassessment on day 5 for the need of an extra dose of 400 mg).

Here, we report our experience on the use of an initial single bolus dose of rFVIIa (180 μg kg−1 in children and 150 μg kg−1 in adults) for the management of mild-to-moderate bleeding episodes in haemophilia A patients with inhibitors.

The initial single dose on Day 1 was followed by a wash-out period of 72 h to determine single-dose PK.

In initial experiments, a single dose of PEG minocycline-liposomes was administered after EAE disease onset at day 15 post-immunization to determine the duration of efficacy of this preparation.

Objective: To evaluate the effects of a single rescue dose of antenatal betamethasone after an initial single course on the frequency of neonatal respiratory distress syndrome and perinatal infectious morbidity in pregnancies complicated with preterm labor and delivery.

Our initial results indicate that a single dose of Lu-PSMA for the treatment of metastatic prostate cancer patients without any other therapy option is safe and seems to have a low early side-effect profile with evidence of positive response to the therapy according to PSA decline in 70%% of patients.

An association was evident between SF2 after HDR and LDR irradiation and the ratio of the absolute level of initial and residual damage after a single dose of 60 Gy.

The interventions consisted of (i) initial health education at study inception and systematic treatment of all individuals aged ≥2 years once every year with a single dose of albendazole; (ii) initial health education and bi-annual albendazole administration; and (iii) bi-annual treatment coupled with latrine construction at family level and regular health education.