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Finally, as psychiatric patients with autism spectrum disorder (ASD) have interestingly been found to prefer robotic to human partners in an initial interaction, though exhibit profound impairments in general mentalizing ability [25], it is possible that this patient group might have facilitated mentalizing when engaging with robotic relative to human interactors.
10) In the Discussion section the authors discuss TRIP13's mode of substrate recognition, which seems to include an initial interaction of the p31 adaptor with the TRIP13 N-terminal domain, before the MAD2 substrate binds in the central pore.
We initialize the families and ages in the model as such because we want to test whether an initial interaction preference for proteins of a similar age will be amplified through a process of duplication and subfunctionalization.
Two different routes of the PIP3 to the PD C2 cleft were observed in the four simulations, two via an initial interaction with the PD and two in which the initial interaction occurs via the C2 domain.
For example, BMAP-27 and BMAP-28, host defense peptides from the cathelicidin family, exhibited lower activity on cancer cells when sialic acid had been cleaved off (Risso et al., 1998) suggesting that the outside charge seems to act as an initial interaction site for the peptides.
Enlist the assistance of an attorney or have a lawyer review your partner company's contract so you know how you will be paid and the basis for payment (for example if it based on produced work, solid sales, sign ups, conversions, referrals, etc).. Follow up with clients after an initial interaction.
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In the absence of ligand, such an aromatic initial interaction could induce a conformational change in the JH2 αC helix and trigger catalytic activity via repositioning of key catalytic residues.
The need for an adequate initial interaction between the 2′P-AMP portion of NADP+/H and FNR that provides subsequent conformational changes leading to CTC formation is further confirmed.
Because the mammalian membrane is deficient in anionic lipids, AMPs cannot undergo a proper initial interaction.
Again, this indicates that our learning method requires prior knowledge about the type of interaction that is lost when using a flat initial interaction setting.
Thus, microscopy of the Ad5-membrane interaction supports the existence of a CAR-dependent initial interaction, succeeded by a closer association via a secondary receptor with 5-fold symmetry, perhaps located in the penton base.
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