Sentence examples for an initial differentiation from inspiring English sources
In addition, coalescent analyses suggest an initial differentiation of the Northeast Asia populations, a bottleneck in Beringia ca. 20,000 years BP, ended with a population expansion in America ca. 15,000 years BP [12], [13].
We therefore examined these populations and surprisingly observed that the EPLMs are strongly increased in percentage and number while the preB1 cell numbers are reduced in the BCS mice, indicating an initial differentiation block at this stage already (Fig. 3A).
Most of the cultured cells showed evidence of an initial differentiation process, suggesting that NO could be acting in a selective way on the total ESC population.
We did not detect an alteration in the initial differentiation of chondrocytes in Mmp13−/− calluses as compared to WT (Fig. 3A), indicating that the difference in cartilage volume observed by day 7 was transient.
In the experimental IL-6 gene knockout mouse, a delay in early induction of IFN γ [23] as well a delay in the initial differentiation of Th1 cells, but not in expansion, has been reported [42].
The elementary genetic mechanism that draws the recessive genes out from the cover of the wild genotype of the natural species also brings about the first domestication-dependent changes and the initial differentiation of a wild species into types that can serve as the basis for breed formation.
Therefore, TCF21 has a transient role in the initial differentiation of Sertoli cells in response to SRY, and then a later role in the initiation of Leydig cell differentiation.
Our work highlighting the early abca12 expression in the EVL seems to support the conclusions that EVL forms the external layer of the embryonic and larval dermis and represents the initial differentiation of a true epidermis (Fukazawa et al., 2010).
The initial differentiation begins within a nasoventral patch.
The starting populations for the migration treatments were initially transferred without migration to allow some initial differentiation between populations.
In summary, multiple pathways, including Erk, Stat3 and Smad, have been shown to participate in cellular decisions for ESC self-renewal or differentiation; this study identifies Shp2 as a critical player orchestrating these pathways in programming initial differentiation of human and mouse ES cells.
