Sentence examples for an initial and substantial from inspiring English sources

There was an initial and substantial rise in the numbers tested and in the measured prevalence of CKD markers from 2002 to 2004.

Although a specialist is still needed to supervise the whole process of oil spill detection, this method gives an initial view, substantial for further evaluation of the scenes and risk estimation.

A significant proportion of treated patients thus either fail to respond or relapse following an initial response, and a substantial number of patients are unable to tolerate treatment [ 10].

Analysing in our study the trend of each singular clinical and laboratory parameter over time, we observed only an initial substantial advantage in adding GC compared with MTX monotherapy in clinical variables, with no persistent differences.

The shape of the squareback geometry is first optimized to make an initial substantial drag reduction.

The proposed SC-RRCSW model combines the advantages of high initial stiffness and substantial energy dissipation provided by the rocking mechanism at the base.

These observations seem at odds with models that posit a competition between ON/OFF cells where one would expect a refinement of simple-cell structure from an initial state of substantial ON/OFF overlap [56], [57].

Indeed, it has been reported that prolonged adrenergic stimulation of astrocytes leads to a biphasic glycogen response, with an initial substantial glycogen degradation, followed by glycogen resynthesis [ 24, 25].

In the proposal the government would collect and hold an initial 28% and return a substantial benefit -- a tax credit -- for job creation.

There is one initial, and rather substantial, difference between philosophers who allow a very large number of categories and those who allow only a very small number.

The comparison of different models of diversification using Bayes factor tests led to the selection of a two-rate pure-birth process and estimated a fourfold decrease in speciation rates (dropping from an initial 0.441 to 0.108), and indicating a substantial slowdown during the Miocene.