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Elevated expression of ApoE mRNA, in conjunction with a lower expression of ApoE protein in those with APOE ϵ4,4 genotype may represent a failed attempt to increase ApoE expression as a way of increasing βAPP expression, which in itself may be futile as ApoE4 has been shown to be an ineffective stimulant of βAPP expression [ 15].
However, elevated PKG protein expression was observed which might reflect an ineffective compensatory mechanism in the LV.
These cell lines contain defective Jak-STAT signaling due to the expression of a truncated IFNAR1 that leads to impaired STAT1 and STAT2 phosphorylation and an ineffective antiviral response.
Blame is an ineffective solution to problems.
This is an ineffective oversight arrangement.
Clearly, the solution to an ineffective 30-second TV spot is not ineffective 10-minute videos.
It's an ineffective use of scarce resources".
Penn State University is plagued by an ineffective board of trustees.
He was an ineffective leader.
An ineffective government under the Taliban regime also contributed to an ineffective health care system [2].
This political domination creates the JRC an ineffective institution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com