The increased path length and clustering coefficient indicated an increased functional segregation and integration of the network topology in migraineurs at the sensor level.
One possible mechanism is an increased functional involvement of early and associative perceptual cortices [17].
In the HG/HI rat, a 48 h glucose infusion results in an increased functional β-cell mass [17].
Eta acts as an inhibitor of sGC; the net result of a downregulation of eta, therefore, would be a relative increase in sGC activity, resulting in increased cGMP and amounting to an increased functional NO signal.
In conclusion, we have demonstrated that an increased functional connectivity within the medial temporal lobe, the frontal lobe, and between the parietal and frontal lobes and a decreased functional connectivity in the DMN areas in patients with mTLE.
However, the key question is whether the conservation of expression patterns of network constituents implies conservation of functional network interactions, and if so, how an increased functional complexity can evolve.
However, perhaps the most dramatic finding in this study was that tethered electrodes were surrounded by an oval-shaped cavity with an area extending that of the original implant, thus causing an increased functional distance between the electrode and tissue.
These data indicate that expression of rEA not only increases the quality and breadth of several antigen specific CMI responses, but also facilitates an increased functional capacity of antigen specific T-cells to kill cells presenting a pathogen specific peptide, in this instance an antigen derived from the HIV-Gag protein.
Whereas some studies give no evidence for an on-going in vivo neutrophil activation [6], [7], others have shown that neutrophils in patients with established CAD or in individuals at high risk for vascular events possess a "primed" character, i.e. an increased functional potential ex vivo compared to neutrophils from healthy individuals [6], [8] [10].
At the end of this phase, there is a decrease in evolutionary rate due to an increased functional constraint [ 6].
