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Hypersusceptibility is an increased predisposition of certain individuals to react to a chemical.
Diabetes, in particular, has become so common (affecting forty per cent of the population) that researchers think that many children, after exposure in the womb, are born with an increased predisposition to the disease.
Patients with the anomaly show an increased predisposition to dyspnea, recurrent respiratory infections and pulmonary haemorrhage.
Female athletes may be particularly susceptible to MDI because of an increased predisposition to joint hyperlaxity.
Atrial fibrillation (AF) is a dysfunction of heart rhythm and represents an increased predisposition to ischemic stroke in AF patients.
Macrosomic infant was associated with an increased predisposition to develop overweight or obesity at the beginning of their childhood.
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This is in agreement with previous studies [23] and may be an effect of the increased predisposition of T lymphocytes to undergo apoptosis in sepsis [24].
MSH6 mutations are rarer than mutations in the other two genes, being found in 10 20% of HNPCC cases, who often have an atypical presentation and increased predisposition to endometrial cancer (22, 23).
This cumulative societal sleep curtailment is significant, as sleep deprivation is associated with a number of metabolic consequences: increased predisposition to obesity (3) and insulin resistance (IR) (4) in both adults and children, increased risk of type 2 diabetes mellitus (T2DM) in adults (5), and higher fasting glucose in young adults with preexisting diabetes (6).
This "metabolically obese" phenotype among normal-weight individuals may explain the increased predisposition for diabetes despite a relatively low prevalence of obesity.
In humans, germ-line mutations of these genes are associated with Rubinstein–Taybi syndrome, an autosomal dominant disorder characterized by physical abnormalities and mental retardation, and associated with increased predisposition to lymphoma.
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