There is good evidence that these benefits are derived from more than just an increased dose of dialysis, as simply increasing urea Kt/V during standard HD to >1.3 does not improve outcomes in the same way.
To compensate for any increased LPV/r clearance resulting from NVP-associated hepatic enzyme induction, an increased dose of LPV/r was used in combination with NVP to aim for comparable therapeutic LPV plasma concentrations in both trial arms.
The magazine still features stories and poems, though fewer, but the noticeable aspect of Gourevitch's revitalised magazine is the reflection of his own literary interests, resulting in an increased dose of reportage.
Data from Experiment 2 indicate that the inhibitory effects of DHTP but not 3α-Adiol can be moderated by an increased dose of EB.
At 1 year an increased dose of DFX was administered (27 ± 6 mg/kg/day vs 20 ± 2 mg/kg/day at baseline, p = 0.01) with a stable dose of DFO (32 ± 4 mg/kg/day).
This hyperphosphorylation of tau was prevented with an increased dose of the antioxidant, previously reported to be sufficient to prevent neuropathology.
Higher levels of the RAD51 binding to the BCR in AT5BIVA cells could be observed after treatment of cells with an increased dose of etoposide (Figure S10).
This further supports the hypothesis that, in our model, perifosine levels are limited by the BBB, and that we might be able to overcome this complication with an increased dose of perifosine.
Patients who required an increased dose of dialysate bicarbonate were summarized in Table 4.
For example, an increased dose of topiramate, up to 100 mg/day, is usually recommended.
Four patients were then entered at dose level 3 and received an increased dose of oxaliplatin (100 mg m−2).
