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The possibility of synthesizing single-crystal graphene on h-BN with appreciable growth rates by adopting a simple CVD approach is a step towards an increased accessibility of this promising van der Waals heterostructure.
In both cases, the improvement of saccharification efficiency is achieved, likely due to an increased accessibility of cellulose to cellulases.
Solubilization of xylan led to an increased accessibility of cellulose to cellulases and thereby increased the hydrolysis extent of cellulose.
Similarly, co-reconstitution of purified MviN and Lipid II in vesicles did not lead to an increased accessibility of NBD-Lipid II for dithionite (Supplementary Figure S9), showing that this protein has no direct role in Lipid II translocation.
The elevated appearance of p18 in the C62S variant of BAX in our experiments may be a result of an increased accessibility of BAX for the responsible protease, which is activated based on the cytotoxic activity of C62S BAX variant.
This assumption is supported by the finding that C-terminal disease mutants bind myotubularin (MTM1) more efficiently due to an increased accessibility of the MTM1 binding site in the open conformation.
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The transparency of zebrafish larvae in combination with an increasing accessibility of fluorescent tools (Ellett et al., 2011; Lawson and Weinstein, 2002; Meijer and Spaink, 2011; Tobin et al., 2012b) provides opportunities to study host-pathogen interaction in real time.
Indeed, the gene encoding CENP-A itself has a strong DHS site upstream of its promoter specifically in SW480 cells but not in HeLa cells, providing a satisfying correlation between increased accessibility of the CENP-A gene promoter, and excess CENP-A mRNA (and subsequently, protein) present in SW480 cells.
Third, there has been a trend towards increased accessibility of climate change data and predictions at finer spatio-temporal resolutions, making it more feasible to do biodiversity climate research.
Similarly, genetic reduction of cytosine methylation in a ddm1 mutalso8,39,40 also caused increased accessibility of the tested fragments (Supplementary Fig. S6).
Clinical staff cited standardization of care delivery as a top priority through increased accessibility of pertinent clinical information, enhanced pain assessment and management, and improved availability of clinical decision-making tools.
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