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These findings must be viewed with caution, however, because power analysis showed low effect sizes and an inadequate sample size.
However, the safety and effectiveness of these approaches are unclear due to limitations in trial design, an inadequate sample size, and the problems inherent in evaluating the effects of initial feeding regimen on necrotizing enterocolitis (NEC) and neurodevelopmental outcome.
This trial had an inadequate sample size to demonstrate efficacy or safety.
This showed that in all cases an inadequate sample size in stroke may account for the lack of significance here (Figure 9; third section, final column).
These results, however, did not reach statistical significance possibly due to an inadequate sample size rather than a true difference was absent.
The difference in survival found - although not statistically significant possibly due to an inadequate sample size - may be rooted in this improved myocardial function.
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A recent survey suggests that only half of institutions routinely collect tissue from native biopsies specifically for EM [ 15], confounded by an inadequate sampling rate.
We wonder whether these conflicting results, of dipluran polyphyly versus monophyly, were caused by an inadequate sampling of diplurans, especially the lack of species from the Projapygoidea.
The major sources of bias were an inadequate sampling method, sampling frame, sample size and response rate and a lack of information to aid interpretation and applicability of the results including reporting of confidence intervals and subgroups.
Indeed, the acceptance probability may become trapped in a local minimum of the potential energy, which may result in an inadequate sampling of the macromolecular states, as seen in the conformational states [ 32, 33].
These successes aside, the utility of molecular dynamics simulations is still limited by two principal challenges [ 27]: the force fields used require further refinement, and high computational demands prohibit routine simulations greater than a microsecond in length, leading in many cases to an inadequate sampling of conformational states.
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