Mitochondrion is another important player that may mediate insulin/IGF-1 or mTOR signaling in aging.
I know what he can give, let's try and get the best and let's try and make him again a very important player that he couldn't be last season".
Alternatively, other important players that affect p53 functioning, e.g. the p53 activator p14ARF or the negative p53 regulators MDM2 and MDM4 (Fig. 2) are deleted or amplified in gliomas, respectively.
In higher plants, besides the conventional phytohormones such as auxin and cytokinin, a group of small secretory peptides, namely the CLAVATA3/EMBRYO-SURROUNDING REGION-RELATED (CLV3/ESR, CLE) peptides, has been recognized as important players that are responsible for mediating cell-to-cell signaling.
Much more likely is that Russia sees them as a base for influence in Kiev, with the expectation that, as things settle down, Ukrainian politics will soon offer opportunities for Moscow to be an important player in that capital, as it has always been in the past; perhaps, in time, to be the dominant player.
As the largest holder of the retail E.T.F., Goldman was an important player in that market, but not the only one involved in hedging.
Groves may have also seen in Oppenheimer a man driven far less by ideology than by ambition, whose need to be an important player ensured that anything he directed would be a success.
Edin, when he came on, did very well and he was an important player at that moment, and to win here you need to play very well with your whole team".
