Sentence examples for an important player in the pathogenesis from inspiring English sources

ET-1 is an important player in the pathogenesis of PAH.

From the above properties, we found NFκB is an important player in the pathogenesis of both cancer and Alzheimer's disease.

Such effects has pointed out IL-32 as an important player in the pathogenesis of inflammatory diseases as atopic dermatitis, Crohn´s disease, rheumatoid arthritis and rhinitis [ 7, 10, 12, 14].

Given the causal association between high serum LDL and coronary stenosis in ACS, we tested the biological interaction between the genotypes and the serum level of LDL-C as an important player in the pathogenesis of the coronary artery stenosis and its severity in ACS patients.

The chemokine CX3CL1 (fractalkine, neurotactin) is unique in that it exhibits properties of both a chemoattractant (the soluble form of the protein) and an adhesive compound (the cell membrane-anchored form); therefore, CX3CL1 is an important player in the pathogenesis of different inflammatory diseases, including atherosclerotic plaque formation [ 9].

While PGC-1 α emerges as an important player in HD pathogenesis, little is known about the involvement of this master coactivator in other polyQ disorders.

Previous studies have suggested the PAG as an important player in migraine pathogenesis [13, 26].

Accidental triggering of uncontrolled, excessive MMP production of MMPs, present in the cells of the secondary epidermal lamellae, presumably for normal remodeling purposes, appears to be an important player in laminitis pathogenesis.

Chemokines, scavenger receptors and adhesion molecules have long been known as important players in the pathogenesis of atherosclerosis.

B cells are important players in the pathogenesis of rheumatoid arthritis (RA) [ 1, 2].

We identified the following important players in the pathogenesis of AD.