Sentence examples for an important mediatory from inspiring English sources
IL-6, a cytokine believed to play an important mediatory role in the inflammatory response to exercise, usually increases following intense and prolonged exercise.
Local administrations were important mediatory nodes in stakeholder networks.
However, in response to an IPC stimulus, the ROS generated by the mitochondria overwhelms the ROS-scavenging capabilities of the mitochondria, the result of which is ROS entering the cytosol where it activates important mediatory kinases implicated in IPC protection.
Crucially, the CYPD component of the mPTP is critical to IPC protection as it is required to generate mitochondrial ROS, which in turn activates the important mediatory protein kinases, Akt, and Erk1/2.
This cardioprotective effect of HPC was found to be dependent on ROS, given that it was abolished in the presence of the ROS scavenger, MPG (23.2 ± 3.5% with HPC vs. 44.1 ± 2.6% with HPC+MPG; P < 0.05), confirming the important mediatory role of ROS in IPC protection.
Yoo et al (2004) suggested that a LTB4-BLT2-linked cascade has a crucial mediatory function in cell transformation induced by oncogenic Ha-RasV12.
Earlier reports also demonstrated the same with the transcription factor NF-κB and c-jun playing a significant mediatory role therein [51], [52].
An important question or an important topic.
Important jobs on an important day.
It was an important development.
