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The phrase "an important differential" is correct and usable in written English.
It can be used when discussing a significant difference or distinction that affects a situation, decision, or outcome.
Example: "The study highlighted an important differential between the two groups, which could influence future research directions."
Alternatives: "a key distinction" or "a crucial difference."
Exact(60)
International travel leads to imported cases in countries of the Northern Hemisphere (1 ), where dengue fever is an important differential diagnosis of fever in travelers returning from the tropics.
Nevertheless, when sea ice forms, it has an important differential effect in that it increases ocean salinity where it forms.
It is an important differential diagnosis in young patients with syncopal attacks and varying degrees of heart blocks.
Nonorganic, functional memory disorder (FMD) is frequent in memory clinic patients, and is an important differential diagnosis to prodromal dementia.
Inflammatory pseudotumor of the liver (IPL) is an unusual tumor-like condition that is becoming recognized as an important differential diagnosis in the patient presenting with liver masses.
The high likelihood that King Tut's parents were siblings means he could have inherited the sickle cell trait from both and suffered from SCD. "Sickle-cell disease is an important differential diagnosis: one that existing DNA material can probably confirm or rule out," conclude Timmann and Meyer.
Bipartite patella is an important differential diagnosis of patellar fracture.
It is an important differential diagnosis in a child presenting with acute stridor or wheezing.
Bronchial branching malformation like BB with or without stenosis is an important differential diagnosis in newborn presenting with respiratory distress.
In contrast, orbital tuberculosis (OTb) is rare but still forms an important differential diagnosis of orbital mass lesions in a high tuberculosis (TB) endemic setting like ours.
We postulated that deep neck abscess is an important differential diagnosis in a patient with meningism and medical treatment may be available for immunocompetent deep neck abscess.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com