Sentence examples for an important contributor in the pathogenesis from inspiring English sources

Autophagy-associated genes (ATG16L1 and IRGM) were also seen in early-onset CD cases, further confirming autophagy as an important contributor in the pathogenesis of pediatric CD. 83 Dubinsky et al 84 examined associations between the R381Q variant of the IL-23R gene and CD in a pediatric cohort and reported significant associations using a family-based study.

Thus, stability also appears to be an important contributor in the DNA melting activity of HPR.

Inflammatory mediators such as TNFα and GM-CSF are secreted by lung epithelium, alveolar macrophages and other inflammatory cells and are thought to be important contributors in the pathogenesis of COPD.

Understanding the structure of a protein is an important contributor in understanding its function.

NGO/religious sources were an important contributor in Niger.

Depression was also an important contributor in young subjects (15 54 years).

Increased use of condoms was also an important contributor in Uganda's HIV prevention programs.

Serum HDL cholesterol was positively associated with serum bilirubin, being an important contributor in women.

25 27 Inflammation has been proposed as an important contributor to the pathogenesis of cardiac dysfunction in RA patients.

Regardless of the bacterial pathogen causing the infection, dysfunction of the host's immune responses to bacterial pneumonia, particularly those involving macrophages in the lungs (i.e., alveolar macrophages) and neutrophils, is an important contributor to the pathogenesis of the disease in people with AUD.

Although PPAR-γ activation has been implicated as an important contributor to the pathogenesis of the toluene diisocyanate induced asthma phenotype in a female BALB/c mice model (Lee et al. 2006), PFOS and PFOA have been shown to significantly increase activation of mouse or human PPAR-α and PPAR-β, but not of PPAR-γ, in vitro (Takacs and Abbott 2007).