Sentence examples for an important component in the pathogenesis from inspiring English sources

C-reactive protein (CRP), the prototype acute phase protein, may represent an important component in the pathogenesis of arteriosclerosis and may also be a target for drug development.

Disruption of any of these essential processes is an important component in the pathogenesis of many diseases, including cancer.

Oxidative stress is widely recognized as an important component in the pathogenesis of AMD [ 26, 27].

Loss of differentiation is an important component in the pathogenesis of many cancers.

Indeed, a disturbed skin barrier is an important component in the pathogenesis of contact dermatitis, ichthyosis, psoriasis, and atopic dermatitis.

It is generally agreed that decreased insulin sensitivity is an important component in the pathogenesis of obesity, type 2 diabetes, hyperuricemia, cardiovascular disease, hypertension and polycystic ovary syndrome [ 1, 2].

Because proinflammatory responses play an important role in the pathogenesis of bacterial meningitis, their modulation may be an important component in the disease management (for review, see the report by Tauber and Moser [ 10]).

Secretory proteins have been shown to be an important component in many biological processes, including pathogenesis of parasites [ 40- 42].

Cytokines' elaborate interplay enables inter-cellular communication and constitutes a crucial part in the regulation of immune and inflammatory processes - two important components in the pathogenesis of GPA - thus allowing an adequate response to microbial challenges.

However, evidence implicates cigarette smoking, oxidative stress and inflammation as important components in the pathogenesis and progression of the disease [23], [24], [25], [26], [27], [32].

The sequestration of MBNL proteins by CUG RNA repeats is established as an important component of the pathogenesis in adult DM1.