Sentence examples for an ile from inspiring English sources

Among the best candidates, an Ile replacement proved best in improving the peptide therapeutic window.

Last summer in France, Fitch and Oka did what they called an Ile Flottante, by building an enormous doughnut-shaped picnic table that could float.

Thus, M112 was mutated to an Ala, and to an Ile (Fig. 7E) to generate the RNF125 mutant detected in some of the overgrowth syndrome patients31.

Strikingly, of these three RING interacting residues, only the M112 equivalent is not present in RNF114 but is an Ile instead (see Supplementary Fig. S1).

An initial set of simulations was performed to investigate a single lid region mutation G230I in hSTING (corresponding residue in mSTING is an Ile), which rendered the protein sensitive to DMXAA.

The simulations found that an Ile side chain was enough to form a steric barrier that prevents exit of DMXAA, whereas in WT hSTING, the Gly residue that lacks a side chain formed a porous lid region that allowed DMXAA to exit.

Binding of STRADα to MO25 involves four interaction sites (sites A D) in STRADα: Glu (site A), Ile (site B), Tyr (site C) and the C-terminal Trp–(Glu)–Phe [W(E F] motif (site D) [ 69, 70].

The hydrophobic residue number is in harmony with the number of hydrophobic residues of the protein (chain A: Ile-50, Pro-81, Val-82, Ile-84; chain B: Pro-81, Val-82, Ile-84).

KFC2b could successfully predict only three of them (A-PHE-442, A-ILE-443, and A-LEU-444), whereas PPCheck could predict all the six hotspots (Fig. 5B).

The first group, from here on named NisA-group, contains a conserved G/A-A/G-x-x-R motif at the C-terminus of the leader peptide and a Ile residue at the first position of the core peptide.

The prefusion-closed conformation of HIV-1 Env has been identified as one such preferred conformation, and a current leading vaccine candidate is the BG505 DS-SOSIP variant, comprising two disulfides and an Ile-to-Pro mutation of Env from strain BG505.