Based on this finding, we hypothesize that the comparative epigenetic analysis of the changes induced by different AML1-MTG fusion proteins in an identical cell context (e.g. the 32D context) might provide a lead to elucidating the differences observed in leukemic cells carrying either one of the two proteins [ 8].
A particular advantage is that cassette exchange events can be performed for comparative gene expression analysis in an identical genomic context to compare individual genes, or complex recombinant constructs, subject to varying genomic influences on transgene expression.
No one has yet described all of the nuances of meaning that can be conveyed by the single word, "yes," even in an identical conversational context (Crystal, 1995, p. 248).
The ultimate aim of these experiments was to analyse the respective characteristics of ERα and ERβ recruitment on the estrogen inducible stably transfected luciferase transgene within an identical cell context.
These cellular models combine the ease of bioluminescence analysis of estrogen inducible reporter transgene transcription with the power of ChIP analysis of both receptors (ERα and β) recruitment in an identical cell context and with the same antibody.
Deep understanding, potential for transfer to new contexts Shallow understanding, potential for transfer to very similar contexts Minimal understanding, potential for knowledge recalled verbatim and in identical context.
Genes a1 and a2 in genome A and can both register as orthologous to gene b in genome B because of segmental duplication in A or because identical contexts of a1 and a2 survived the fractionation process intact since the early polyploidization process.
We compared different policies in identical contexts (an approach rarely used before now) to better understand the factors underlying their success or failure and particularly what role the common substratum, i.e., the health system and its provision of services, played in the results.
In addition, a post-hoc statistical analysis was carried out between the dialogs with identical contexts but varying accentuation patterns.
Here, we report the comparison of protein splicing between 20 different inteins from various organisms in identical contexts to identify robust inteins with foreign exteins.
