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It is believed not to be an extrinsic effect, but rather a basic phenomenon related to the nature of aSi H and to the stability and motion of Hrelated species in the aSi H lattice.
As well as direct effects of telomerase defects within haematopoietic stem cells, telomerase dysfunction in BM stroma has an extrinsic effect on HSCs, inhibiting HSC and progenitor function and replication [84].
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As an indirect extrinsic effect, when infected individuals are released into the community and become infectious to others, recently quarantined individuals may be detected and isolated earlier than those who have not been quarantined [ 47].
In concordance with results from the peripheral blood, the GFP− population also showed an increase in myeloid BMCs as sign of a cell extrinsic effect driving the myeloid expansion.
In contrast, ITK SYK enhanced myeloid cells and reduced B220+ cells within the GFP+ and GFP− population, pointing towards a cell extrinsic effect as driver for myeloid expansion and B-cell suppression in those mice.
This latter difference might reflect a B-cell extrinsic effect.
To distinguish between the intrinsic and extrinsic effect microscopic strain measurements (Synchrotron X-ray diffraction) were compared with macroscopic measurements of the mechanical hysteresis loop.
Due to the extrinsic effect of crack branching and deflection, the resistance to FCP of β-annealed Ti64 specimen was higher than that of mill-annealed counterpart in low and intermediate ΔK regime at both R ratios of 0.1 and 0.7.
In this context, the polymorphism of NQO1 gene involved in benzene activation and participating in benzoquinone detoxification and reactivating benzene intermediates, might contribute to outgrowth extrinsic effect in exposed cells [ 20].
The receptor is present on various cell types within the retina, and the secreted protein could potentially be beneficial in affecting RGCs in an autocrine manner as well as by other cells in a paracrine manner by having extrinsic effects on the RGCs.
The latter property has proven difficult to quantify on a materials basis because it depends on extrinsic effects.
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