The phrase "an extremely significant" is correct and usable in written English.
It can be used when emphasizing the importance or impact of something in a particular context.
Example: "The discovery of the new species is an extremely significant advancement in our understanding of biodiversity."
Alternatives: "a highly important" or "a very crucial".
He said: "This is an extremely significant outcome.
He called the initiative "an extremely significant part of my plan to improve that service".
John Scillia, president of Garden State Engineering, a private engineering company, and an expert on storm water runoff, called the rules "an extremely significant change".
"It is an extremely significant diversion from the core mission of this agency," said the commissioner of the agency, Linda I. Gibbs.
On the open market, it is said to be worth more than £1m and is an "extremely significant" find, according to Sir Nicholas Serota, director of the Tate.
Dan Creed, vice president of marketing for BMW of North America, said, "We're in the middle of an extremely significant product offensive".
"It is an extremely significant loss because the state invests a great deal in their health, education and wellbeing and loses them at their time of greatest productivity for society".
"It is an extremely important development with potentially significant impacts on the economy, the natural setting of the bay, and wildlife".
Brunner Munzel analysis revealed an extremely highly significant association between decline in performance on the spatial task and lesioned voxels which span a region from IPS (most dorsal MNI coordinates: –51, –49, 48) to TPJ (Fig. 7).
Compared to the negative control group, there was a highly or extremely significant reduction in paw oedema in all drug-treated groups (P < 0.001 for ethosomes, P < 0.01 at day 10 and 13 and P < 0.001 at day 15 and 18 for liposomes, resp).
When we correlated the values of PM2.5 during the entire period with the %MCN of active exposure, we observed a positive and extremely significant correlation (r = 0.818 p = 0.004), corroborating the results obtained by Batalha et al. [ 46], Carvalho-Oliveira et al. [ 29], Carreras et al. [ 43] and Prajapati & Tripathi [ 47].
