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During her PhD with Prof. Igor Lubomirsky and Prof. Meir Lahav, she developed an extremely sensitive technique for detecting deviations from symmetry in crystals in order to improve our fundamental understanding of crystal structure, function and different growth mechanisms.
ICP-MS is an extremely sensitive technique capable of detecting metal fragments approaching 1 part in 1012 (parts per trillion) and was extremely valuable in identifying iron as the predominant heavy metal in the IOFB; copper was found in minimal quantities.
Quantitative real-time PCR is an extremely sensitive technique that enables validation of selected candidate miRNAs.
The band-shift assay is an extremely sensitive technique that is particularly suited to study high-affinity DNA-protein interactions such as HMGB1 binding to hcDNA [21], [22].
NGS has become the new method of choice for gene expression experiments as it is an extremely sensitive technique which has allowed for global analyses of exceptionally large datasets from transcriptomic, proteomic, metabolic, regulatory and developmental pathways to create networks that categorize interactions and function of organs or molecules at varying complexity levels [ 52].
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In addition to classical techniques (western blot, ELISA) that make use of specific anti-HMGB1 antibodies, we present here a new, extremely sensitive technique that is based on the fact that hemicatenated DNA loops (hcDNA) bind HMGB1 with extremely high affinity, higher than the affinity of specific antibodies, similar in that respect to DNA aptamers.
The Baradar story touched on the I.S.I.'s relationship with Taliban leaders—an extremely sensitive subject.
SV is an extremely sensitive electrochemical technique in which the substance is preconcentrated by electrodeposition at a controlled time and potential into a small-volume electrode.
In this respect, it must be emphasized that extremely sensitive techniques might detect very low levels of mutant EGFR that are not associated with sensitivity to EGFR tyrosine kinase inhibitors.
Although traditional PCR is an extremely sensitive (97%) and specific (100%) technique compared with microscopy, with the ability to amplify low levels of infection, it is limited at the POC by a susceptibility to contamination, expensive reagents, and the need for a stable power supply and thermocycler.
It will take an extremely sensitive telescope and very clever techniques to see it, but we have the technology now to build such machines.
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