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Discrete model M8 (in which the ω value can vary according to a beta distribution (between 0 and 1) and which includes an extra category of sites with ω>1), was compared to model M7 (in which ω can only vary according to the beta distribution).
A more conservative likelihood ratio test for positive selection replaces the M7 null model with M8a, which has an extra category of ω fixed at one.
The Missing Indicator Method is applied to categorical exposures and includes an extra category of the exposure variable for those individuals with missing data.
The first model set contains a neutral (null) model M1a allowing two categories of sites, one with ω = 0 and one with ω = 1, and model M2a that adds an extra category of sites with ω > 1.
The second includes a neutral (null) model M7 assuming that ω is β-distributed among sites and model M8 that adds an extra category of sites with ω > 1 [ 46].
Similar(55)
The categories consisted of each oligonucleotide of the set of reference oligonucleotides plus an extra category consisting of all other oligonucleotides combined.
While I feel attractive and confident, I am also in the "a little extra" category of body type, as a size 14-16, woich won't appeal to everyman.
However, the addition of an extra category (i.e., R = 0.0625) may be beneficial (Table S4 and Figure S7).
In all adjusted analyses we performed sensitivity analyses to check for the effect of missing values on outcome by adding an extra category with missing values.
For the small proportion of patients with missing status for smoking, BMI, and alcohol intake, "missing" was included as an extra category.
Missing values (generally <2%) were accounted for by creating an extra category in each covariate.
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CEO of Professional Science Editing for Scientists @ prosciediting.com