Sentence examples for an extensive change from inspiring English sources

During the last hundred years European landscapes have experienced an extensive change in structure including a substantial loss of wetland habitats.

To accomplish this, he immediately ordered an extensive change of administrative personnel.

In addition, morphological alterations are also accompanied by an extensive change in their protein profiles.

However, adding several care providers to a multidisciplinary care team implies an extensive change to usual care.

It seems a small number of large-scale recombination events cannot cause an extensive change in skew correlation.

In this respect, TCR triggering with antigen MHC complexes is known to trigger an extensive change in the T-cell transcriptional program [ 18].

Now, as Lt. Gov. David A. Paterson prepares to succeed Mr. Spitzer, Republicans and Democrats alike are predicting an equally extensive change of atmosphere and, for better or worse, a return to comity between the governor and the Legislature.

While specific prediction about what the new world will look like is hard, the general prediction that we are entering into a period of extensive change seems trivially obvious.

The selectors tried to turn things around with seven new faces in the team, the most extensive change of an England XI during a Test series since seven players were changed for the 1921 Ashes Tests against Australia at Lord's and Headingley (when only JWHT Douglas, Ciss Parkin, Lionel Tennyson and Frank Woolley were retained, and Tennyson replaced Douglas as captain).

The book is important because it demaded extensive change at an early stage (1989) and it directs this demand not only towards politicians, but to society as a whole.

The correlation between some imprinting methylation in tumour and normal tissue means that cfDNA originating from tumours could also potentially be used for this type of work but there is an extensive epigenetic change in tumours, and cfDNA may not always be relevant to investigations of cancer-predisposing epigenetic change in normal tissues.