This was expected because the IFG-IGT group has more severe metabolic abnormalities than the isolated states (15) and therefore has an increased risk of progression to diabetes.
If the distribution of IFG-7 were indeed random, we would expect that the distribution of clones lacking IFG-7 elements (i.e., lacking hybridization signal) would approximate normality; in such cases, the mean number of clones expected to lack an IFG-7 element and the theoretical standard deviation (SD) can be estimated using Theorem 2 of Holst [46].
Hence, the observed number of clones lacking IFG-7 hybridization is 161 times (13926/86 = 161) the expected standard deviation for a normal distribution, strongly reinforcing our hypothesis that the distribution of IFG-7 is not random.
As observed in earlier studies among Kuwaitis [ 12, 17], and as would be expected, age was found to be an important predictor of IFG and diabetes prevalence for both genders in the present study.
As expected, the progression from NGT to IGT and/or IFG exhibits striking sex differences [ 24- 26].
In practice, given the relatively low prevalence of IGT or IFG (15%), compared with 30% expected, clustering was less common than predicted.
5 Within PODOSA, the prevalence rate for IGT and/or IFG was approximately 15%, much lower than expected.
As expected in young Gambian adults there was a low prevalence of hypertension (<3%), IFG (<1%) and type 2 diabetes (<1%).
If so, involvement of the regions that had been noted in relation to social processing, including IFG, middle frontal gyrus (MFG), and PHG29,30 would be expected.
